Glossary

Amino acids
Amino acids are biochemical building blocks. They form short polymer chains called peptides or polypeptides which in turn form structures called proteins.

Antibody
Antibody is a protein used by the immune system to identify and neutralize foreign objects like bacteria and viruses. Each antibody recognizes a specific antigen unique to its target

Antigen
Antigen is any molecule that is recognized by antibodies. Usually, an antigen is a protein or a polysaccharide, but it can be any type of molecule, even small molecules if coupled to a large carrier (haptens).

APC
APC’s are a group of cells of the immune system that are capable of presenting epitopes to and activating lymphocytes.

B lymphocyte
B lymphocyte is a special white blood cell involved in the humoral immune response by producing antibodies.

Chagas
Chagas disease, also known as American trypanosomiasis, is a tropical disease. In most cases, humans are infected by strain Trypanosoma cruzi II, which is mainly transmitted by Triatominae insects (a.k.a “vinchuca”, “kissing bugs”, or “assassin bugs”), blood transfusions and organ transplantations

Complement
Complement is a group of proteins of the complement system, found in blood serum which act in concert with antibodies to achieve the destruction of non-self particles such as foreign blood cells or bacteria.

CTL
CTL’s are cytotoxic T cells (CD8+) that destroy infected cells. These cells function as 'killer' or cytotoxic cells because they are able to destroy target cells which express specific epitopes that they recognize.

Epitope
Epitope is a fragment of an antigen that is recognised by the immune system and targeted by antibodies, cytotoxic T cells or both.

HTL
HTL’s are helper T cells (CD4+) that act as "middlemen" in the immune response. When they get activated, they proliferate and secrete cytokines that regulate or 'help' other lymphocyte cells function.

Peptides
Peptides are the family of molecules formed from the linking, in a defined order, of various amino acids. The link between one amino acid residue and the next is an amide bond, and is sometimes referred to as a peptide bond.

Phagocyte
Phagocyte is a cell that ingests (and destroys) foreign matter, such as microorganisms or debris via a process known as phagocytosis, in which these cells ingest and kill offending cells by cellular digestion.

Protein
Protein is a complex organic compound that consists of amino acids joined by peptide bonds. Proteins are essential to the structure and function of all living cells and viruses